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Oven Roasted Pork Tenderloin Recipe

This simple, but delicious pork tenderloin is rubbed with garlic, mustard, horseradish, and Italian herbs before being pan seared and finished in the oven.
Course Dinner
Cuisine American
Prep Time 15 minutes
Cook Time 45 minutes
Total Time 1 hour 10 minutes
Servings 30 slices
Calories 256kcal
Author Heather Dessinger



  • Preheat the oven to 325°F.
  • Season the pork tenderloins on all sides with salt and pepper.
  • In a small bowl, mix together the mustard, horseradish, Italian seasoning, and garlic.
  • Rub the mustard mixture all over the pork.
  • In a large cast iron skillet or other oven safe pan melt the 2 tablespoons of butter.
  • When the pan is hot, add the seasoned pork tenderloin.
  • Brown on all sides.
  • Transfer the pan to the preheated oven and cook for 35-45 minutes until a meat thermometer inserted in the center reads 145°F.
  • Remove the meat from the oven and let rest 10-15 minutes until slicing and serving.


If the pan you are browning the pork in on the stove is not oven proof, you can simply transfer the meat to a baking pan before putting it in the oven.


Serving: 3slices | Calories: 256kcal | Carbohydrates: 0.8g | Protein: 34.1g | Fat: 11.9g | Saturated Fat: 4.8g | Cholesterol: 113mg | Sodium: 246mg | Fiber: 0.2g | Sugar: 0.2g