DIY Hyaluronic Acid Serum Recipe

Heather Dessinger

This post contains affiliate links.
Click here to read my affiliate policy.
hyaluronic-acid-serum-recipe

I eat skincare. Wait, that didn’t come out right. I mean skin food . . . or food for vibrant skin, like bone brothgelatin, and naturally-derived vitamin C.

When it comes to supporting collagen production and skin elasticity, there’s no better approach than nourishing skin from within.

That’s because collagen – despite how often it’s used in face creams and serums to make them more marketable – can’t be absorbed via topical application. Collagen molecules are too large to penetrate the outer layer of skin, but you can provide your body with the basic building blocks to optimize its own production through food.

HOWEVER, that’s not to say that topical formulations can’t do amazing things for your skin. 

Hyaluronic acid, for example, is what makes babies skin look so dewy and plump. Our skin makes less of it over time, but we can apply it topically to provide intense hydration. In this article I’ll share a super simple recipe for hyaluronic acid serum that you can incorporate into your skincare routine, but first you might be wondering . . .

diy-hyaluronic-acid-serum

What exactly is hyaluronic acid?

While collagen and elastin are the main proteins that provide structural support for our skin, hyaluronic acid is like a gel-cushion that holds in moisture. This naturally occurring polysaccharide has the ability to absorb up to 1,000 times its weight in water, and when applied topically it can help skin hold in moisture and feel more supple. (1)

High molecular weight hyaluronic acid is also considered helpful for reducing inflammation and supporting tissue repair. (2) (3)

However, in the skincare world, low-molecular weight hyaluronic acid (LMW-HA) is often touted as superior because the smaller molecules are able to penetrate the skin’s surface. It’s made by breaking high molecular weight hyaluronic acid into fragments using enzymes.

So which one is better? 

Low Molecular Vs. High Molecular Weight

While it’s true that low molecular weight hyaluronic acid does penetrate skin, it’s also well-documented in clinical research that low-molecular weight hyaluronic acid is actually pro-inflammatory rather than anti-inflammatory. (3)

Some doctors believe that while LMW-HA may make skin appear more supple at first, the effect may be due to inflammation rather than hydration, and could lead to accelerated aging. (4) It’s interesting to note that babies primarily make the high molecular weight form. (5)

Now, you might be thinking “What about high molecular weight hyaluronic acid – is it beneficial or similar to collagen . . . too large of a molecule for skin to absorb?”

In terms of topical benefits, it’s agreed that if nothing else, high molecular weight hyaluronic acid is an amazing moisturizer. 

However, according to this study, full-size (high molecular weight) HA does actually penetrate skin. 

Here’s what cosmetic chemist, Perry Romanowski, had to say on the subject.

Why is this so surprising? Two reasons. First, hyaluronic acid molecules are too big. They’re about 3,000 nm in diameter and the space between skin cells is only about 15 to 50 nm. Theoretically there’s no way a molecule that large should be able to make its way through the skin. Second, hyaluronic acid is very hydrophilic, or water loving, and we know that to penetrate skin substances have to be more oleophillic, or oil loving. (6)

And yet, according to the above study, it does. More research needs to be done, but it’s interesting.

Should I add essential oils?

You can add a 1% dilution (about 12 drops) of a skin-friendly essential oil such as lavender, frankincense, or helichrysum if you’d like.

However, I prefer not to because I apply the serum liberally around my eyes and it tends to run a bit. (Essential oils + Eyes = Not Good)

homemade-hyaluronic-acid-serum-recipe
Print Pin
4.20 from 41 votes

DIY Hyaluronic Acid Face Serum Recipe

Perfect for all skin types, this DIY hyaluronic acid serum hydrates and nourishes skin. We make less hyaluronic acid as we grow older, which is why topical application makes such an impact.
Prep Time 5 minutes
Total Time 5 minutes
Calories
Author Heather Dessinger

Equipment

  • small jar with lid
  • measuring cup
  • measuring spoon

Ingredients

Instructions

  • Place powder in a small clean jar.
  • Pour in distilled water and glycerin or leucidal if using.
  • Place a lid on the jar and shake well. It will look very chunky at this point, but don’t worry. As the hyaluronic acid absorbs the water the consistency will become more smooth.
  • Place in the fridge for several hours (or overnight) to allow it to thicken before use.

Notes

Shelf life: Without a preservative I store my serum in the fridge and use within two weeks. With a preservative it can be stored at room temperature for up to three months.

How To Use Your Hyaluronic Acid Serum

After washing your face with a gentle cleanser, pour or scoop a little bit the serum from a clean jar into your hands. Only a very thin layer should be applied – otherwise it will flake and peel off. It’s best not to dip your hands directly in the jar because it may reduce the shelf-life.

Ideally, this HA serum would be applied both in the morning and before bed. If you use skin toner, put it on after the toner and before moisturizer.

Important Tip: Hyaluronic acid is humectant, which means it draws moisture to itself. That’s part of what makes it amazing, but something to be aware of is that in dry climates where there isn’t much moisture in the air, it’s possible that hyaluronic acid could draw moisture from deeper layers of the skin upwards toward the surface.

To avoid this, I prefer to moisten my face and neck before applying hyaluronic acid. This way it has plenty of water to bind to. Then, after the serum dries I add a layer of this hydrating skin repair serum or my favorite store-bought tallow balm to seal in moisture.

FREE Ebook: DIY Body Care Gifts Made Simple

Do you want to give gorgeous, handcrafted gifts for family and friends, without spending a bunch of time on them?

Then I’d love to give you a free copy of DIY Body Care Gifts Made Simple – my step-by-step guide to making gorgeous skincare products without stressing yourself out – as a gift for signing up for my newsletter. I’ll show you how to make vintage labels, luxurious lotion bars, lip balms, sugar scrubs, body sprays and more like a pro. Sign up for my newsletter and you’ll be redirected to the download page immediately!

  1. Alina Maria Holban and Alexandru Mihai (2016) Nanoarchitectonics for Smart Delivery and Drug Targeting
  2. Litwiniuk, Malgorzata et. al. (2016) Hyaluronic Acid in Inflammation and Tissue Regeneration
  3. Ruppert, S.M. et. al. (2014) Tissue integrity signals communicated by high-molecular weight hyaluronan and the resolution of inflammation
  4. Dr. John Sanderson and Dr. George Taylor. Hyaluronic Acid: Yes, Size Does Matter
  5. Vinukonda, Govindaiah et. al. (2016) Hyaluronidase and Hyaluronan Oligosaccharides Promote Neurological Recovery after Intraventricular Hemorrhage
  6. Romanowski, Perry (2015) Is hyaluronic acid a good anti-aging ingredient? 

Related Posts

About HEATHER

Heather is a holistic health educator, herbalist, DIYer, Lyme and mold warrior. Since founding Mommypotamus.com in 2009, Heather has been taking complicated health research and making it easy to understand. She shares tested natural recipes and herbal remedies with millions of naturally minded mamas around the world. 

4.20 from 41 votes (32 ratings without comment)

Leave a Comment

Recipe Rating




216 thoughts on “DIY Hyaluronic Acid Serum Recipe”

  1. I knew it! I knew you must be working on a recipe for this because you love all the best things and, obviously, this is one of the best things!!! Thanks! Thanks! Thanks! Can’t wait to make this.

    Reply
  2. What do you moisturizer your skin with before applying the serum? I have an oil based moisturizer and tallow balm, and that’s all I use on my face…
    thank you!! This sounds amazing and I’ll give it a try as soon as I order the products!

    Reply
      • Do you mean you moisten your skin with water? Or do you use a moisturizer before and after applying? Sorry, I’m still confused!

        Reply
        • I moisten my skin with water, apply the serum, allow my face to dry, and then seal in the serum with an oil-based moisturizer. 🙂

          Reply
          • Okay ladies, water is not good for skin. Tap water used to rinse you face after cleansing contains particulates and contaminants, well water less so. Use a natural toner on cotton pads to remove all cleanser residue, loosed pore debris, leftover makeup, waste by-products, pollutants, allergens that the cleanser missed, AND tap water residue that is so very dehydrating. This toning “skin water” creates proper hydration that will be sealed in with your moisturizer.

          • Heather, I was wondering if you still recommend a toner to be used before applying the acid and repair serum? Thanks!

      • Heather,
        I commented twice on this but didn’t get any response. The first time i made the hyaluronic acid i used distilled water and put it in a small glass mason jar. It stayed gelled for about a week then turned watery. I still used it and it tightened up my face. The next time it only stayed gelled for a day then went watery. I changed to a smaller glass container and decreased the recipe by 1/2 and it stayed gelled for 2 weeks. I just made it again and it went watery after the first day. I added the hyaluronic acid first then the distilled water and shook it up and placed in the fridge. I don’t use the glycerin or preservative and always keep it in the fridge. What do you think?? Really like it but feel like i must be doing something wrong. Thanks for answering this question! I would really appreciate some input!!

        Reply
    • So the first time i made this i used 1 tsp hyaluronic acid to 7 T water and it came out gel like. Since then it initially gels up but quickly becomes like water after storing in refrigerator overnight. Then i put it in a spray bottle and spritz it on my face. It tightens up my face. Should it be more gel like and what can i do to change that. Decrease the water. I have well water

      Reply
      • I used your recipe and the same thing happened. It was gel like a few hours later but then became like water the next day. I think it still works- oh, and i used distilled water this time. Any thoughts? Is this normal? So i put it back in the little spritzer bottle and spray it on.

        Reply
        • Hi Cheryl, I’m so sorry that happened. After speaking with one the hyaluronic acid powder sellers I think I understand what is going on. Although similar in name, Leucidal Liquid and Leucidal Liquid SF are different, and that is causing the problem.

          You want to use Leucidal Liquid SF for the hyaluronic acid serum.

          Reply
      • I didn’t use glycerin or the preservative and kept it in the refrigerator and it turned watery the next day. Still ok to use? It tightens up my face. I spray it on. The first time i made it it was more gel like for almost a week. Any help would be appreciated!

        Reply
  3. Hi! Thank you so much for all your wisdom!!! Do we use either the glycerin or the other preservative? Or are we suppose to use both? Thank you!!

    Reply
    • Hi Tracy, glycerin can sometimes serve as a preservative, but only when it comprises about 50% of the recipe. I wouldn’t consider it to have any preservative properties in this recipe. 🙂

      Reply
    • I recommend not mixing in any oil. This is a water-based formula and will not mix properly. Instead, I suggest applying this serum and allowing it to dry, then layering an oil-based moisturizer over it to help seal it in.

      Reply
  4. Been following you for awhile, love many of your posts, but…hands down this is my my favorite DYI post ever! Thank you sooo sooo much, Heather! You are genius! I cannot wait to try it and will check in when I do 🙂

    Reply
    • 1. Cleanse
      2. Pat skin dry
      3. Moisten skin, e.g. with toner on a cotton ball/pad, or rose water spray, or both
      4. Apply hyaluronic acid serum to moist/damp skin
      5. Allow to dry
      6. Apply essential oil-based serum, any other kind of serum, or moisturizer.
      7. Finish with something oil-based (not just essential oil-based), such as tallow or fractionated coconut oil, jojoba oil, etc., to seal the skin barrier, and lock-in the hyaluronic acid especially. (So the hyaluronic acid can bind with moisture in the deeper layers of the skin, and stay there, instead of drawing moisture in the opposite direction, out of the skin, as explained in the article.)

      Reply
  5. Hi!
    I just wanted to take a moment to compliment you on your blog. I am a reformed and retired (I’m now a stay at home mom to four boys) Pharmaceutical Sales Representative. For many reasons, I have abandoned the pharmaceutical approach to helping me raise a healthy family. Your attention to documentation and research is what I find refreshing and what keeps me coming back for reference all the time. Thank you. It is so important, please keep it up. The more that people are exposed to that information (and understand where it comes from), the less grip “industry” can have over our health.

    Reply
    • Great comment! I love hearing professionals from the industry confirming the benefits of natural approaches based on experiences with modern medicine/pharmaceuticals. Thanks for sharing your thoughts!

      Reply
      • Hi
        Ok I must be doing something wrong
        I’ve left in fridge overnight
        Next day it’s even thicker and I had to actually scoop it out and My face was flaky
        Little help here?

        Reply
        • Hi Tabby, it should have a gel-like consistency so it doesn’t sound like you are doing anything wrong. However, if it’s flaking on your face it’s likely that it was over-applied. My suggestion would be to try using a lot less and see how it feels. 🙂

          Reply
          • Heather,
            I used the recipe and followed it exactly. It had a gel like consistency for a few hours and then got watery. I mixed it in a small mason jar. What am i doing wrong?? I spray it on and it tightens my face but as thin as water

          • Can we substitute the water with 100% pure aloe vera gel (like from Lakewood Juices)?

            Thank you for a great formula!

  6. Hi Heather, I do want to try this but am somewhat unsure if it will irritate my skin I am a fair skinned person have sun damage. Most things I use on my face like coconut oil do irritate my skin. I use a chlorinated filter in my shower and only moisturize with minimal jojoba oil. This works well for me. I guess I’m asking if you think this may irritate my pre-cancers or maybe help them heal a bit. I do use a homemade face mask of bentonite clay mixed with some charcoal powder and various other things and that really helps. Any ideas? Also if you were to add the vit C powder, which one would you recommend? Thanks for any help you can give.

    Reply
    • It shouldn’t irritate your skin. Your body makes it’s own hylauronic acid, but it lessens with age. Coconut oil is highly comedogenic, which means it can clog pores. Consequently, it may actually make acne worse for some people.

      Reply
  7. Thanks so much for this recipe! I am hoping to make some HA serum this weekend, as soon as the products arrive from Amazon 🙂 The seller suggested a recipe which included Vitamin C, glycerine, and Ferulic Acid. Apparently the FA stabilizes the C and adds more photo-protection, and some form of it has been patented by a major skincare company because the results of this combo are pretty fantastic.

    Unfortunately, that recipe was a bit murky about how to add the FA; it suggested “a couple drops dissolved in an alcohol base.” I’ve looked high and low on YouTube, Google, etc., and haven’t found any other well-written recipe that includes all of those ingredients. Would you consider researching this and providing us with the kind of reliable and safe recipe for which you are so famous? Thank you!!

    Reply
    • Hi Alison,
      I saw the recipe you were talking about and had the same concerns. While looking at some of the ingredients to buy I came across a little more detail about this, the alcohol base would be vodka and just enough to make a paste. Add the vitamin C to water then the ferulic acid paste and glycerin, mix well until dissolved and then add the HA powder. I hope you find this helpful, I’m going to give it a try. 🙂

      Reply
  8. Hi there! First off, thank you for all your posts! I started following you before I became a mother and everything you post has greatly helped and influenced my decisions. And my daughter is a very healthy 2 year old! I am wanting to use this recipe but I am pregnant and wanted to know if there is any contraindication to use this during pregnancy. Thank you!

    Reply
    • Organic hydrosols are gentler than essential oils with different constituents. One of nature’s best gifts for the skin, psyche and body! Great as a face toner too.

      Reply
      • Possibly, but Vitamin C breaks down quickly in water unless it is stabilized, so you’d need to look into how to do that before adding it to this recipe.

        Reply
      • So grateful for all this information! I already purchased a liquid form of hyaluronic acid in hopes of incorporating it into my diy facial serum. I used a combo of eo’s and sweet almond or jojoba oil. After reading your post I’m thinking I should not add this HA to it. Would you agree? Maybe use it separately?

        Thank you!

        Reply
    • I have been making this recipe, and it always comes out great and works like a charm. The last time I made it, however, I forgot to put it back in the refrigerator, and the next morning it had lost its consistency. Do you know why this would have happened? The temperature in my house was about 62-63, so I don’t understand why it would have turned to water again.

      Reply
  9. HI. I followed the receipi but my batch is very thick gel like. When I put it on my skin it is ball up. No absorbing. Kind of like peeling. So I just added a little more water, stirred and put it back in the fridge. The receipi I followed came with my packaging

    7 tsp water
    1 tsp hyaluronic acid pdr
    1/2 tsp glycerin

    Shake and refrigerate

    Any suggestions. I am also taking 1/16 tsp twic a day. Thanks much

    Reply
    • The recipe on this site calls for 4 tbsp water (almost twice what you used) and 1/2 tsp HA (half what you used). Sounds like you figured out a solution by adding more water. Good to know what it does with too little water though!

      Reply
    • Could be there’s fillers in your hyaluronic acid powder that are changing its consistency…

      Your ratios are also super off. The original recipe is about 24 times more water than hyaluronic acid.

      Reply
  10. Hi Heather,

    the links for the hyaluronic acid you provide do not ship to my country.
    But I was able to find one online that sells local to me . Only thing is it doesn’t state if it is high or low, when I emailed the seller they sent me a document with the products specs and it says it has a molecular weight of : Min. 0.8×106 Da
    Do you know if this is considered high or low?
    thanks

    Reply
  11. Like another commenter, when I use this it peels/flakes. What am I doing wrong? Feels like heaven on my skin so I only use at night for this reason.

    Reply
    • Hi Lesley, I’ve had that happen if I apply too much. Try using less and I think you’ll find that it’s no longer an issue. 🙂

      Reply
  12. I made this per the posted recipe but had mold growing in it within days – even with the Leucidal liquid preservative added. I poured a small amount into my hand when using and did not dip my fingers into the serum. (which was in a small mason-ball jar) It was not refrigerated but on my bathroom counter for 5 days- weather has been cool here in Colorado. I loved the serum but couldn’t not believe it molded in such a sort timeframe. Any suggestions short of refrigeration? Is there a better preservative to use?

    Reply
    • I’d love to know what kind of consistency y’all have who can “pour it”. Mine is very gelatinous and I followed your recipe to a T!

      Reply
  13. I make this with rose water and vitamin C and store it in the fridge. For a short time (a few weeks), it has this great gel-like consistency. But then it goes flat and become watery. Does it lose its efficacy? How do I keep the consistency gel-like? Thanks!

    Reply
    • Hi Rose, do you substitute rose water for the distilled water? Did you add the glycerine? I am looking for a rose water hyaluronic acid serum recipe. Thanks!

      Reply
  14. Thanks for sharing this recipe. I was wondering if one could use aloe vera (juice or gel) instead of water to dissolve the powder?

    Reply
    • Vitamin E is a great antioxidant that can prevent some oils from going rancid quickly, but it doesn’t have any antimicrobial properties and is not a true preservative.

      Reply
  15. High molecular weight HA does not penetrate the epithelium. Very low molecular weight HA, which does penetrate the skin efficiently, can induce a pro-inflammatory response. Recent data indicates that solutions of low molecular weight HA [50 kDa] are best suited for topical use in skin care products as it can penetrate into the skin well but does not cause inflammation.

    This information comes from the Bulk Actives site and has cited studies.

    Reply
  16. I’ve been using Hyaluronic Acid for a while. So far I am very pleased with the Lady Soma Renewal Serum (which contains hyaluronic acid) with it. No funky smell or stickiness. I have a combination skin type: dry and oily in t-zone area. My trick is to apply when my face is still wet when it feels really dry cause of the dry weather in California or apply right before.

    It helps my skin hydrated better this way without breaking-outs.

    Reply
  17. Hi heather
    i just read ur reciepe and really like it . i wanna know that can i add to my serum authenthic aloe vera gel???thanks in advance

    Reply
  18. At the bottom of your recipe you mention an optional natural preservative. Might I suggest Colloidal Silver as the preservative? I manufacture my own C.S. and it’s made with distilled water and it has worked wonderfully in my serum. I’m going to use your recipe with that one change.

    Reply
    • Hi! I want to use colloidal silver as a preservative in my diy facial mist toner. it will be in a 2oz bottle, comprised of mostly hydrosols, plus one glycerin based extract. How much silver do you recommend to use for a 2 oz bottle of water based toner? I was also thinking of preserving my hydrosols in the fridge with a bit of silver in each ingredient. Thanks!

      Reply
  19. Do you think you could use a plant hydrosol to replace the distilled water for added benefit? I was thinking tea tree or helichrysum. Just curious, I don’t want to do something to change or contaminate the original recipe. I don’t use the preservatives, I just make a small amount every two weeks and keep in the fridge. Also, what are your thoughts on hydrosols in general? Thanks!

    Reply
  20. Why couldnt you use a small amount of apple cider vinegar as a preservative? After all AVC diluted down is used as toner or even a face wash. Lots of good things in ACV even topically if used correctly. 🙂

    Reply
  21. Hi Heather!

    I want to make this serum and also an oil blend serum. Would the hyaluronic acid serum go on before a nourishing oil blend? Do you have a recipe for a face oil blend to leave on over night?

    Thank you!

    Reply
    • Hyaluronic acid requires water as a base and lip balms are typically a mixture of oils, butters and waxes, so unfortunately in general the two are incompatible.

      Reply
  22. Good morning! Thank you for all you post! I made the hyaluronic acid concoction and want to know if I could use Argan oil or Marula oil on my face as a moisturizer after putting this on? Do you have anything recipe wise for sunscreen that is a very simple recipe?

    Reply
  23. According to current Cosmetic Data (2018) — Hyaluronic Acid is a large molecule whether it is high or low molecular weight and as such it does NOT penetrate deep into the skin, rather it hydrates the surface layers. Hyaluronic Acid does however play an important role in delivering actives through the skin as it acts like an osmotic pump. I don’t know where you got your information from but I am a formulator and what you are claiming is not accurate regarding hyaluronic acid absorption.

    Reply
    • Hi again!

      I saw somewhere that you can add 10% nicotinamide powder to a DIY hyaluronic acid serum. Would I need to increase the water?

      Hoping you’ll answer the aloa vera substitution for the water, it looks like it’s been asked several times. 🙂

      Thanks!

      Reply
  24. Hi. Thus looks like an awesome recipe. I’m curious where the HA acid is sourced from. Do you have any info on that? Thank you.

    Reply
  25. Thanks for this recipe, retail Hyaluronic acids can be very pricey. I am wondering if ascorbic acid (vit C powder) could be added for both the vitamin value and as a preservative. Any thoughts on that?

    Reply
    • Vitamin C is not very stable and will break down unless you add something else to stabilize it. (Refrigeration and wrapping the bottle in aluminum will help slow down the breakdown. So will keeping it in a syringe so air can’t oxidize the vitamin C.)

      Reply
  26. I made this serum and it was so easy and inexpensive. Love it! I live in a dry climate, so thank you for the tip about moistening my face first.

    You have a great website with loads of helpful information. Please keep it up.

    Reply
    • Unfortunately it has a gel-like consistency that is too viscous for a dropper bottle. You can thin it out with water but that will likely decrease the shelf life. I am not familiar with the preservative you linked to so I’m can’t say how it would work, sorry!

      Reply
  27. Hi Heather, thanks for the lovely blog it’s very informative. Was wondering if I could use mixture of flower hydrosol and distilled aloe Vera juice instead of distilled water .

    Reply
  28. Hyaluronic Acid is a natural glycosaminoglycan or GAG (a type of carbohydrate molecule) it has the ability to moisturise and plump the skin without making it feel greasy, congested or irritated, so it can be utilised by pretty much all skin types – it comforts and relieves tightness in dry skin during the Winter and moisturises and soothes oily skin during the Summer, which is why it is included in everything from face masks and moisturisers to hand creams and serums.

    Reply
    • Vitamin E is an antioxidant but not a preservative. It can help extend shelf life by slowing down the reaction of oils with oxygen in the environment, which eventually leads to oxidation. However, it doesn’t have any antimicrobial properties and therefore cannot be used as a preservative.

      Reply
  29. Hi, I am using hyaluronic acid gel with a contouring device. The gel allows the device to glide smoothly over the skin – but I use gallons of the stuff – which really increases the cost of using the device. Do you have a gel version of the DIY hyaluronic acid serum recipe?
    Please & Thanks,
    Donna

    Reply
    • Hi, I want to try this. But if I click your links I dont see hyuloronic acid powder but all kind of serums and make up, so I dont know what to buy?
      Can jou help me?
      Or just Google hyuloronic acid powder high weight ? What is the name of te brand?
      Kind regards Deborah (netherlands)

      Reply
      • Hi Deborah, when I link to a product that is available in the U.S. but not in a reader’s country (in your case, the Netherlands), Amazon will show product results that are similar but not identical. Unfortunately I don’t know of a brand of high molecular weight hyaluronic acid powder to recommend specifically, but yes I think if you search Amazon for “high molecular weight hyaluronic acid powder” there is a good chance what you need will come up.

        Reply
      • @Regina: Water, filtered or unfiltered has lots of minerals in it. Which might have a negative result for the skin. Unfiltered can also have chlorine and fluoride or other things that would not be good for the skin.
        Distilled water is water that has been stripped of all minerals and additives that your city might add in, or that your well might have in its natural state.
        That is why it is used here. Hydrosols are also, due to their making, basically distilled water with herbal properties of what was used to make it (rosewater: roses, lavender, etc.)

        Reply
    • I tried to make a batch with filtered water, and it didn’t come out right for some reason. I threw it out and made another with distilled water, and it was perfect.

      Reply
  30. I make my own face cream. After making your recipe for this serum, how much would I add to my 4 ounce jar of face cream? Usually I make 1 cup of face cream with my recipe, so how much would I add to one cup of my face cream recipe? Can I add the powder to my recipe without adding water?

    Thank you for your help,
    Becky

    Reply
  31. Hi Heather
    I saw this hyaluronic acid on Amazon (Simply Essential )and they say:
    “MOLECULAR BLEND | This is the only Hyaluronic Acid which blends small, medium, and large Hyaluronic Acid Molecules. Molecular Weight Blend: 240k, 480k, and 800k Daltons”
    Do you think this would be better? It is $66 for 10 grams.
    Thankyou.

    Reply
  32. Hi Heather,

    I cannot obtain your recommended HA powder in my country, and am opting to use a 1% HA solution instead (1% sodium htaluronate (1000 kDa), 1% phenoxyethanol, 98% distilled water).
    I usually use a mere 2-5% of this solution in a serum. How would you recommend I use this solution in this recipe?

    Reply
  33. Hey, this recipe looks like a good excuse to finally go and get my hyaluronic acid! I’ve been reading about it for ages, but this recipe seems so easy! It’s on my to-do list now! Only one question; I’ve tried Leucidal as a preservative a long time ago and it doesn’t work as well as it should. Do you have any recommendations on a different type? Since it’s water based product, I can’t imagine doing this recipe without a proper preservative; after all, I want my skincare to be safe :). Thanks!

    Reply
  34. Is there a reason your recipe is different from the one provided on the HA jar? The BOS HA instructions are 1 tsp to 1/4 c water. Just wondering about why the 1/2 tsp vs 1 tsp amount difference? Maybe it’s bc your recipe is adding preservatives?

    Cant wait to try! Ty for any info!

    Reply
  35. First of all, I love your site. Just wondering if you’ve ever come across a hyaluronic mouthwash recipe?

    Reply
  36. I was wondering if freezing would negatively effect a hyalauronic acid serum?
    I’m going to try making one with aloe gel, (I’ll let you know if it works!) and it would be great if I could make a big batch and unfreeze it as necessary

    Reply
  37. Can you help. I made this recipe and it turned out perfectly I thought. Several days later it had turned to liquid not a serum anymore. Must I keep in fridge for it to stay thick?

    Reply
  38. The links are broken just an fyi 🙂
    Also, whatever acid brands you are referring to are they safe while breastfeeding? I see alot of hyaluronic acids with all kinds of other stuff in it and am unsure if it’s ok.
    Thank you!

    Reply
  39. One comment mentioned “Ferulic Acid”. What is it and where can I get it?
    Did you try the recipe you said you found and how did it work compared to this recipe?
    Thank you for the information.

    Reply
  40. I thought I left a comment yesterday but don’t see it. I ordered my HA and would like to know if I can use grapefruit seed extract as preservative. I plan to make my serum with rose water which will add benefits. Is that ok? And do you think a pump bottle would work? Thank you for your wonderful recipes.

    Reply
  41. So, I just wanted to say thanks for this. I have made this several times over the past 2 years. I make it as directed, but in a smaller batch to avoid waste. I also include the optional items and essential oils. I store it in the fridge in a glass jar while it gels, then I put it in a glass pump bottle for daily use, keeping it in the fridge the whole time.
    I LOVE THIS STUFF! I have made it for my mom and sister, eventually sending all the supplies for my sister to make her own. I use it after my shower. I spray on a hydrosol, immediately apply this hyaluronic acid, and follow up with my own blended skin serum for moisturizing. I love how my skin feels. I love knowing what I am putting on my skin and how much money I save.

    Reply
      • I use rose water to make the serum. I don’t understand the second question. I apply a thin layer directly to the skin and wait for it to dry before applying oil or cream. The grapefruit seed extract worked well as a preservative.

        Reply
  42. I made my serum but haven’t used it yet. I see why it wouldn’t work in a pump bottle, very thick gel. I added 1/4 teaspoon of grapefruit seed extract since that is all I have at the moment. I will remove small amounts to a tiny jar and leave the rest in the refrigerator. I will keep you posted on how long it keeps this way. It looks awsome. Thanks.

    Reply
  43. HELLO HEATHER,

    I finally made the Hyaluronic acid following your recipe but when I used it for the first time my face was burning.

    I straight away washed it with cold water and the burning went away.

    Could you advise why this happened?

    Thank you so much,
    Martina

    Reply
    • Hi there I’m starting my own lip gloss brand and I have been doing my research on some of the ingredients to put into the gloss which includes versagel, coconut oil, Hyaluronic acid, glycerin, carrot seed oil, mica powder and essential oil but I don’t know if it will mix well together. Do you have any tips that you don’t mind sharing? Thank you!

      Reply
  44. Hi there!

    Any experience with and/or thoughts about using this on a baby with eczema? I have read that hyaluronic acid is good for eczema for helping to hydrate the skin. So, I’m wondering what you think about this recipe for uses beyond one’s facial care routine.

    Additionally, what is the purpose of the glycerin in the recipe?

    Thanks!

    Reply
  45. Hi Heather,

    Would love to make this serum asap but,unfortunately, I already bought my HA from Microingredients on Amazon.The company states that their HA molecular weight is 0.9~1.5Mda.That sounds high to me.Do you think it will be safe to use?
    Also,their recipe is 1 ts of HA per 3.5 oz of water,which is way less HA than your recipe (some people use 1/8 ts per 1 oz water).
    I don’t plan on adding any preservatives as I will make very small batches to last 1 week or even less.
    Thank you.

    Reply
  46. Wow! You have a lot of commenters, Heather! I am wanting to know about this comment you made: In the skincare world, low-molecular weight hyaluronic acid (LMW-HA) is often touted as superior because the smaller molecules are able to penetrate the skin’s surface. It’s made by breaking high molecular weight hyaluronic acid into fragments using enzymes.

    If I want to buy instead of make hyaluronic acid, how would I know whether it is LMW-HA or not? Seems almost better not to risk it, if the label doesn’t say?

    Reply
  47. It rally depends on how you describe LMW-HA. If not described in daltons then its up to the reader to interpret the meaning and actual size. Usually HA is not described in nm, mm, or mesh size but rather in daltons specifically. Ive actually read this scholarly article from NCBI. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486775/
    The takeaway being that HA between 50 – 1,000 kDa is beneficial for the skin, with ~130 kDa being the best according to human studies. And according to Lotioncrafters 130kDa is referred to as extra low molecular weight HA. So according to clinical studies if you stay above 80kDa and below 130kDa you will experience the best results not inflammation.

    Reply
  48. Hi there! Wondering if this serum would be able to be added to the whipped tallow balm recipe? Are there reasons to keep them separate and if so, what are they? Thank you!

    Reply
  49. Hi Heather
    I’ve made your serum 5x now and every time I do it gets moldy. Whether in the fridge or not. With or without preservative. Please help!
    Thanks.

    Reply
  50. 5 stars
    Thank you so much for sharing this recipe! I’ve been buying HA on Amazon for a reasonable cost, but now I’ve got a ton of glass bottles with eye droppers clanking around in my drawer. I save them, because I think it might save me from having to buy a plastic bottle at some point in the future, but I think I have more than enough right how. I’m looking forward to exploring your site a little more.

    Reply
  51. Hello Heather
    I wanted to make your Hyaluronic Acid Serum recipe and the company I ordered it from sent Glycolic Acid. Can it be made with Glycolic Acid?
    Thanks for your reply

    Reply
  52. Hi. I tried to connect to your link for the powder. I am in Canada. It was going to allow to order. I decidedI needed 2 containers. Then I was no longer able to reach the product. I think it is because I am in Canada and must use Canadian amazon. Can you please point me to a source for this product our a similar one that is available Canada?

    Reply
    • I personally wouldn’t unless you speak with a gynecologist first. Vaginal pH is likely very different than skin pH and the moist environment may be more vulnerable to microbe issues (this recipe uses a
      mild natural preservative).

      Reply
  53. Hi Heather! I love reading your blogs! I made this serum, followed all of your application instructions as far as applying to wet skin and sealing with a tallow lotion and it is really drying out my face. I’ve been using it for about 2 weeks, thought I’d stick it out and see if it got better but it is not getting better. I was thinking of making another batch with less HA powder. Do you have any insights?
    Thanks!
    Johnnie Ann

    Reply
  54. Hello Heather, I am very happy with all the recipes I tried except with the
    Hyaluronic Acid Serum. After a night in the fridge, it is gel-like but turns
    into a watery consistency by the next morning.
    Now I have 2 questions: can it still be used in its watery state, or must it be gel-like? For the next batch, I shall try adding Leucidal.
    Could you please send the link? Thank you

    Reply
  55. What do you think about ingesting Hyaluronic acid, like the popular “Infuse” powder by Beauty Society? Good idea, or no?

    Reply
  56. Heather,

    Before I get to question, I’d like to thank you for using sources AND citing them in this article. I’ve ready many a post where people claim to show how something is good or important but fail to support what they say. So, keep bringing us information that is supported by research. I am into by your DIY Hyaluronic Acid Serum Recipe. However, I have a couple questions. The list of ingredients mentioned glycerin as optional but the instructions state to use glycerin or water. I must asume that one or the other is required. Right? Or am I missing something. The second question is about ¼ tsp Leucidal Liquid SF preservative (optional). There is another product similar to this but is called Leucidal Liquid SF complete. What is the difference? Can these be used interchangeably? Thank you!

    Reply
  57. Hi I was looking at your recipe for hyaluronic acid serum and the instant cart says it’s not a complete recipe. Can you be more specific about brands or
    if the hyaluronic acid is powdered or liquid
    Thanks
    Leslie

    Reply